Crown Peptides

Research Peptides

VIP Research Peptide

A high-purity research peptide studied in gut, immune and vascular research. Available in 5mg, with every batch independently tested and dispatched from the UK.

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Product Overview

A high-purity research peptide studied in gut, immune and vascular research. Available in 5mg, with every batch independently tested and dispatched from the UK.

Full Product Specification
Overview

Product Overview

VIP peptide UK is Crown Peptides' vasoactive intestinal peptide, a naturally occurring 28-amino-acid neuropeptide, supplied in 5mg vials for laboratory research into VPAC1/VPAC2 receptor biology and neuropeptide signalling.

5mgAvailable strengthHPLC testedChromatographic purityMS verifiedIdentity confirmedBatch CoADocumentation supplied

Supplied for laboratory research purposes only — not for human consumption or for medical, veterinary or diagnostic use.

Key features

Key Features

  • Studied in research involving VPAC1/VPAC2 receptor biology
  • Studied in research involving vascular and smooth-muscle signalling
  • Studied in research involving gastrointestinal neuropeptide research
  • Studied in research involving immune and inflammatory signalling
  • Batch-specific quality documentation available
Background

About VIP Peptide UK

VIP, or Vasoactive Intestinal Peptide, is a naturally occurring 28-amino-acid neuropeptide that signals mainly through VPAC1 and VPAC2 receptors. It is broadly distributed in neural, gastrointestinal and vascular systems and is therefore used in research spanning several areas of physiology.

Research

VIP Research

VIP research examines VPAC receptor pharmacology, cyclic-AMP signalling, smooth-muscle responses, vascular biology, gastrointestinal secretion and motility, neuropeptide signalling and immune regulation. In a mouse model of induced colitis, VIP reduced both the clinical and tissue-level severity of intestinal inflammation while lowering inflammatory cytokines including TNF-alpha, IL-1 and IL-6 (Learn more). Because VPAC receptors occur across multiple tissues, VIP is particularly useful for studying how the same peptide signal produces different responses depending on cell type and receptor expression, alongside related neuro and signalling-research peptides such as [Selank] and [DSIP].

  • VPAC1/VPAC2 receptor biology
  • Vascular and smooth-muscle signalling
  • Gastrointestinal neuropeptide research
  • Immune and inflammatory signalling
Specifications

Specifications

Product
VIP
Classification
Vasoactive intestinal peptide, a 28-amino-acid neuropeptide
Available strength
5mg
CAS number
40077-57-4
Molecular weight
3325.79 Da
Molecular formula
C147H238N44O42S
Sequence
HisSerAspAlaValPheThrAspAsnTyrThrArgLeuArgLysGlnMetAlaValLysLysTyrLeuAsnSerIleLeuAsn-NH2
Purity and assay
99% (HPLC), batch-specific — refer to Certificate of Analysis
Verification
HPLC and Mass Spectrometry where analytically appropriate

Compound-level reference data. Batch-specific results appear on the Certificate of Analysis.

Work out concentration with the peptide calculator
Testing

Purity and Testing

Crown Peptides VIP is supplied for controlled laboratory research with batch-specific analytical documentation. High-Performance Liquid Chromatography (HPLC) can assess chromatographic purity, while Mass Spectrometry provides molecular information used to support identity verification. The batch-specific Certificate of Analysis is the definitive source for the exact purity result, identity data and analytical specification of the material supplied.

Storage

Storage Conditions

  • Store unreconstituted material at -20°C ± 5°C in a cool, dry environment
  • Prepared research solutions should use validated storage conditions appropriate to the compound and study design
  • Protect from unnecessary heat, direct light and repeated temperature fluctuations
Full storage guide
Related

Related Compounds

Researchers working with VIP may also be interested in [Selank], [DSIP], [Kisspeptin-10], [ARA-290] and [Semax] — other neuro and signalling-research peptides studied in related research areas.

Compliance

Research Use Only

  • Laboratory research only
  • Not for human or clinical use
  • Not for human or veterinary consumption
  • Qualified personnel only
Questions

VIP Frequently Asked Questions

What does VIP stand for?

VIP stands for Vasoactive Intestinal Peptide.

What is VIP?

VIP is a naturally occurring 28-amino-acid neuropeptide that signals mainly through VPAC1 and VPAC2 receptors, supplied by Crown Peptides in 5mg vials.

What is VIP researched for?

Research includes vascular signalling, smooth-muscle biology, gastrointestinal pathways, neuropeptide signalling and immune regulation.

Which receptors are associated with VIP?

The principal receptors are VPAC1 and VPAC2, both of which are G-protein-coupled receptors.

How is VIP tested?

Peptide identity and purity can be assessed using HPLC and Mass Spectrometry, with exact batch values recorded on the Certificate of Analysis.

Read the batch certificate before you order

Every batch is published openly — identity, purity and batch number, with no account needed.

View lab reports

Supplied for laboratory research purposes only — not for human consumption or for medical, veterinary or diagnostic use.

All Batches Purity Tested

Each batch undergoes internal analytical verification using chromatographic and spectrometric methods prior to lyophilisation.

• HPLC Analysis
• Mass Spectrometry Confirmation
• Batch Traceability

For Research Use Only

By purchasing this product you confirm that you are a qualified researcher and that this compound will be used exclusively for laboratory research purposes.

Not for Human Consumption

This product is not intended for diagnostic or therapeutic use.

Any human or medical use is strictly prohibited.

Store Safely at All Times

Store in a cool, dry, secure and sterile environment away from any unauthorised persons or children.

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Further reading

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Disclaimer: All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorised purposes, or unlawful application is strictly prohibited. Crown Peptides UK disclaims all liability for improper use, handling, or regulatory non-compliance.

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