Crown Peptides
0
Check a batchEvery vial has a published certificate. Look yours up by batch number.Peptide calculatorWork out reconstitution and insulin units in seconds.Free UK delivery over £100Order before 2pm for same-day dispatch.
Browse by research area
Performance & Recovery23 compoundsMetabolic23 compounds Neurocognitive16 compoundsImmunology17 compoundsRegenerative21 compoundsLongevity & Cellular22 compoundsEndocrine & Hormonal15 compoundsGastrointestinal & Gut10 compounds
Check a batchEvery vial has a published certificate. Look yours up by batch number.Peptide calculatorWork out reconstitution and insulin units in seconds.Free UK delivery over £100Order before 2pm for same-day dispatch.
Guides and tools
Peptide CalculatorReconstitution and insulin unitsStorage InformationTemperature, light and shelf lifeUnderstanding Quantitiesmg, mcg and what the label meansFAQsOrdering, delivery and testingArticles & InsightsResearch guides for every compound
Check a batchEvery vial has a published certificate. Look yours up by batch number.Peptide calculatorWork out reconstitution and insulin units in seconds.Free UK delivery over £100Order before 2pm for same-day dispatch.
SAVE25%
MOTS-C peptide UK 10mg, 40mg and 50mg vial

Research Peptides

MOTS-c Research Peptide

A high-purity research peptide studied in metabolism and mitochondrial research. Available in 10mg and 40mg, with every batch independently tested and dispatched from the UK.

£24.99or from £18.74 per vial in packs of 10
Save up to 25%
From: £24.99
Your selection:
Batch level verified
View the COABundlesCalculator
All Batches TestedEvery batch, no exceptions
HPLC & MS VerifiedFull certificate published
Same Day PostageOrder before 2pm
UK Based CompanyDispatched from the UK
Product Overview

A high-purity research peptide studied in metabolism and mitochondrial research. Available in 10mg and 40mg, with every batch independently tested and dispatched from the UK.

Full Product Specification
Overview

Product Overview

MOTS-C peptide UK is Crown Peptides' mitochondrial-derived 16-amino-acid peptide, available in 10mg and 40mg strengths for laboratory research.

10mg & 40mgAvailable strengthsHPLC testedChromatographic purityMS verifiedIdentity confirmedBatch CoADocumentation supplied

Supplied for laboratory research purposes only — not for human consumption or for medical, veterinary or diagnostic use.

Key features

Key Features

  • Studied in research involving mitochondrial-to-nuclear signalling
  • Studied in research involving cellular energy metabolism
  • Studied in research involving glucose-utilisation pathways
  • Studied in research involving metabolic stress-response research
  • Batch-specific quality documentation available
Background

About MOTS-C Peptide UK

MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. Its discovery contributed to the concept that mitochondrial DNA can generate short bioactive peptides involved in communication between mitochondria and the rest of the cell.

Research

MOTS-C Research

MOTS-C research centres on mitochondrial signalling, metabolic stress adaptation, glucose utilisation, AMPK-related pathways and communication between mitochondria and the nucleus. In the landmark study that first identified the peptide, MOTS-c prevented diet-induced obesity and insulin resistance in mice through AMPK activation in skeletal muscle (Learn more). It also influences cellular energy metabolism [NAD+], making it an important tool in mitochondrial-derived peptide research.

  • Mitochondrial-to-nuclear signalling
  • Cellular energy metabolism
  • Glucose-utilisation pathways
  • Metabolic stress-response research
Specifications

Specifications

Product
MOTS-C
Classification
Mitochondrial-derived 16-amino-acid peptide
Available strengths
10mg and 40mg
CAS number
1627580-64-6
Molecular weight
≈ 2174.6 g/mol
Molecular formula
C101H152N28O22S2
Sequence
MRWQEMGYIFYPRKLR
Form
Research material supplied according to product label
Purity and assay
99% (HPLC), batch-specific — refer to Certificate of Analysis
Verification
HPLC and Mass Spectrometry where analytically appropriate

Compound-level reference data. Batch-specific results appear on the Certificate of Analysis.

Work out concentration with the peptide calculator
Testing

Purity and Testing

Crown Peptides MOTS-C is supplied for controlled laboratory research with batch-specific analytical documentation. High-Performance Liquid Chromatography (HPLC) can assess chromatographic purity, while Mass Spectrometry provides molecular information used to support identity verification.

The batch-specific Certificate of Analysis is the definitive source for the exact purity result, identity data and analytical specification of the material supplied.

Storage

Storage Conditions

  • Store unreconstituted material at -20°C ± 5°C in a cool, dry environment
  • Prepared research solutions should use validated storage conditions appropriate to the compound and study design
  • Protect from unnecessary heat, direct light and repeated temperature fluctuations
Full storage guide
Related

Related Compounds

Researchers working with MOTS-C may also be interested in [NAD+], [SS-31], [Epitalon], [5-Amino-1MQ] and [L-Carnitine] — other compounds studied in cellular energy, metabolism and longevity-related research.

Compliance

Research Use Only

  • Laboratory research only
  • Not for human or clinical use
  • Not for human or veterinary consumption
  • Qualified personnel only
Questions

MOTS-C Frequently Asked Questions

What is MOTS-C?

MOTS-C peptide UK from Crown Peptides is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region.

Why is MOTS-C important in mitochondrial research?

It is part of a class of mitochondrial-derived peptides that provide evidence for signalling communication between mitochondria and other cellular systems.

What is MOTS-C researched for?

Research includes energy metabolism, glucose utilisation, metabolic stress responses and mitochondrial-to-nuclear signalling.

Is MOTS-C encoded by nuclear DNA?

No. It is associated with a short open reading frame within mitochondrial DNA.

How is MOTS-C tested?

Peptide identity and purity can be evaluated with HPLC and Mass Spectrometry, with sequence and molecular data confirmed on the batch documentation.

Read the batch certificate before you order

Every batch is published openly — identity, purity and batch number, with no account needed.

View lab reports

Supplied for laboratory research purposes only — not for human consumption or for medical, veterinary or diagnostic use.

All Batches Purity Tested

Each batch undergoes internal analytical verification using chromatographic and spectrometric methods prior to lyophilisation.

• HPLC Analysis
• Mass Spectrometry Confirmation
• Batch Traceability

For Research Use Only

By purchasing this product you confirm that you are a qualified researcher and that this compound will be used exclusively for laboratory research purposes.

Not for Human Consumption

This product is not intended for diagnostic or therapeutic use.

Any human or medical use is strictly prohibited.

Store Safely at All Times

Store in a cool, dry, secure and sterile environment away from any unauthorised persons or children.

Other Research Peptides

5-Amino-1MQ research compound UK 10mg and 50mg vial - Crown Peptides
≥99% PURITY
HPLC & MS TESTED
5-Amino-1MQ Research Compound
From: £24.99

Buy Now
AHK-Cu 100mg research peptide vial – Crown Peptides UK
≥99% PURITY
HPLC & MS TESTED
AHK-Cu Research Peptide
From: £29.99

Buy Now
AOD-9604
≥99% PURITY
HPLC & MS TESTED
AOD-9604 Research Peptide
From: £34.99

Buy Now
ARA-290 research peptide UK 10mg vial - Crown Peptides
≥99% PURITY
HPLC & MS TESTED
ARA-290 Research Peptide
From: £39.99

Buy Now
Completed Orders
0 +
VERIFIED PURITY
0 +%
UK Research Supplier
No. 0
ORDER DISPATCH
0 hr

Further reading

UK research peptides. Every batch HPLC and MS verified, certificate published in full.

Products

Research PeptidesPeptide BundlesLaboratory Supplies

Lab Research

Lab Reports / COAArticles & InsightsFAQsAbout Crown Peptides

Customer Service

Contact UsPrivacy PolicyShipping PolicyReturn Policy

Get in Touch

Info@crownpeptides.co.uk+44 7301 802654
SUPPORT Mon to Fri, 9am to 5pmDISPATCH Cut-off 2pmEMAIL Info@crownpeptides.co.ukWHATSAPP +44 7301 802654

Disclaimer: All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorised purposes, or unlawful application is strictly prohibited. Crown Peptides UK disclaims all liability for improper use, handling, or regulatory non-compliance.

© 2026 Crown Peptides UK, a trading name of Crown Peptides Ltd (company no. 17068950), Suite Ra01, 195-197 Wood Street, London E17 3NU . All Rights Reserved.